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UPATERO 15 ER Tablets

UPATERO 15 ER Tablets

*To be consumed as directed by physician.

Therapies:

Rheumatology

Composition:

Each UPATERO 15 ER extended-release tablet contains:

Upadacitinib 15 mg

About UPATERO 15 ER Tablets

UPATERO 15 ER is a prescription medicine containing Upadacitinib 15 mg, used to manage selected chronic inflammatory and autoimmune conditions affecting the joints, skin, spine and digestive tract.

Upadacitinib is a Janus Kinase (JAK) inhibitor that primarily targets JAK1-mediated signalling pathways involved in immune responses and inflammation.

By reducing selected inflammatory signals, it helps control disease activity and associated symptoms in eligible patients.

Its extended-release formulation provides gradual drug release and is generally administered once daily when the prescribed treatment requires a 15 mg dose.

UPATERO 15 ER Tablets

*To be consumed as directed by physician.


Usage Instructions

  • Take UPATERO 15 ER only as prescribed by your doctor.
  • Swallow the tablet whole with water. Do not crush, split or chew.
  • It can be taken with or without food.
  • Take it at approximately the same time each day.
  • Do not change the prescribed dose or discontinue treatment without medical advice.
  • Attend regular follow-ups and laboratory monitoring as recommended.

Note: Dosage and treatment duration depend on the medical condition, treatment response and individual risk factors.


Benefits and Use

Upadacitinib is used to manage selected immune-mediated inflammatory conditions.

Rheumatoid Arthritis

  • Helps reduce joint pain, swelling and stiffness.
  • Supports improved mobility and physical function.

Psoriatic Arthritis

  • Helps control joint inflammation and associated symptoms.
  • May improve joint function and skin manifestations.

Atopic Dermatitis

  • Helps reduce eczema-related inflammation and itching.
  • Supports improved control of skin symptoms.

Ankylosing Spondylitis

  • Helps manage inflammatory back pain and stiffness.
  • Supports improved spinal mobility.

Non-Radiographic Axial Spondyloarthritis

  • Helps reduce inflammation affecting the spine and sacroiliac joints.
  • Supports improved movement and physical function.

Ulcerative Colitis

  • Helps reduce intestinal inflammation and associated symptoms.
  • Supports the achievement and maintenance of remission.

Crohn's Disease

  • Helps manage intestinal inflammation and gastrointestinal symptoms.
  • May help achieve and maintain clinical remission.

Important: These are therapeutic applications of the upadacitinib molecule. The approved indications for UPATERO in India must be confirmed from its current prescribing information.


Safety Information

Important Warnings

  • Serious infections: Increased risk of tuberculosis and other bacterial, viral or fungal infections.
  • Cardiovascular events: Risk of major cardiovascular events, including heart attack and stroke.
  • Blood clots: Risk of deep vein thrombosis, pulmonary embolism and other thrombotic events.
  • Malignancy: Warnings include lymphoma and certain other cancers.
  • Gastrointestinal perforation: Seek medical attention for severe or persistent abdominal pain.
  • Laboratory abnormalities: May affect blood counts, liver enzymes and cholesterol levels.

Common Side Effects

Upper respiratory infections, nausea, headache, acne, herpes zoster and changes in laboratory values.

Precautions

Inform your doctor about existing infections, tuberculosis, hepatitis, cardiovascular disease, blood clots, cancer, liver or kidney conditions, pregnancy and other medications.

Pregnancy and Breastfeeding

Upadacitinib may harm an unborn baby. Effective contraception is recommended during treatment and for the period specified in the prescribing information afterward. Breastfeeding is not recommended during treatment or for the specified period after the final dose.

Medical Monitoring

Regular blood tests, liver function tests, lipid monitoring and infection screening may be required.

Seek immediate medical attention for chest pain, sudden breathlessness, stroke symptoms or signs of serious infection.


Ingredients

Active Ingredient:

  • Upadacitinib 15 mg.

Inactive Ingredients:

Pharmaceutical excipients that support tablet stability and extended drug release.

The complete list of inactive ingredients should be verified from the approved UPATERO package insert.


How to Use

  • Step 1: Consult your doctor and follow the prescribed dosage.
  • Step 2: Swallow the tablet whole with water. Do not crush, split or chew.
  • Step 3: Take it at approximately the same time each day, as prescribed.
  • Step 4: Attend regular medical follow-ups and recommended laboratory tests.
  • Step 5: Report unusual symptoms or suspected side effects to your doctor.
  • Step 6: Do not stop, restart or change treatment without medical advice.

Storage Information

  • Store according to the temperature instructions on the product label.
  • Keep tablets in their original packaging.
  • Protect from excess heat, moisture and direct sunlight.
  • Keep out of reach of children.
  • Do not use after the expiry date or if the packaging is damaged.
  • Consult a pharmacist for safe disposal of unused medicines.

The exact storage temperature must be confirmed from UPATERO's approved product label.

Disclaimer

UPATERO 15 ER is a prescription-only medicine. This information is for educational purposes and does not replace professional medical advice. Use only under medical supervision and refer to the approved Indian prescribing information for complete indications, dosage, contraindications and safety details.